Camel Milk is Rich with Anti-inflammatory Agents


Camel milk is widely used for its reported anti-diabetic and health promoting effects. Lipids derived from the milk have also been shown to exhibit potent anti-inflammatory effects. The mechanism through which these lipids and constituent fatty acids exert these effects remains elusive. images (5)

This paper demonstrates the ability of camel milk lipids to regulate gBSA-induced macrophage inflammation in vitro, by modulating the expression of key inflammatory regulators such NF-kB and NLRP3 inflammasome subunit.

“Results: Gas Chromatography-Mass Spectrometry (GC-MS) analysis found that TL was 96% triacylglycerol (TAG) while the TFA comprised 65% saturated and 35% unsaturated fatty acids. Both TL and TFA significantly (p<0.05) decreased gBSA-induced secretion of pro-inflammatory cytokines (Tumour necrosis factor-(TNF)-α, Interleukin-(IL)-1β/18). TL also demonstrated the ability to regulate the expression of p50/p65 sub-units of Nuclear Factor-kappa B (NF-κB), while concomitantly increasing the expression of regulatory cytokines IL-10, IL-1 Receptor Antagonist (IL-1Ra) and Cluster of Differentiation 163 (CD163)-shifting cells towards an M2 macrophage phenotype. Additionally, we found that TL significantly regulated the expression of Nucleotide-binding oligomerization domain-like receptor family pyrin domain containing-3 (NLRP3) inflammasome subunit and its regulator; Ten-Eleven Translocation-2 (TET-2).”451b4a095abcc0a9ff95ce9ec9578609

 

For detail, please go to the link below.

Author: Dr Raziq

I’m PhD in Animal Agriculture, currently working as a Technical Manager at Al Ain Farms for Livestock Production, Camel dairying, Alain, UAE. I had performed as a Professor and Dean, at the Faculty of Veterinary and Animal Sciences, Lasbela University of Agriculture, Water and Marine Sciences Pakistan (LUAWMS). I work on and write for the subjects of ‘turning camel from a beast of burden to a sustainable farm animal’, agricultural research policies, extensive livestock production systems, food security under climate change context, and sustainable use of traditional genetic resources for food and agriculture. Iim advocating camel under the theme of CAMEL4LIFE and believe in camel potential. I’m the founder and head of the Society of Animal, Veterinary and Animal Scientists (SAVES), and Founder of the Camel Association of Pakistan. I also work as a freelance scientist working (currently member of steering committee) for Desert Net International (DNI). I’m an ethnoecologist, ethnobotanist, Ethnovet and ethomedicie researcher and reviewer. I explore deserts and grazing lands for knowledge and understanding.

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